Case Report: A Woman with Fever, Acute Changes in Mental State, and Progressive Neurological Degeneration


Vol 4 | Issue 3 | Sep-Dec 2018 | page: 17-20 |Carrillo-Torres Orlando, Rivero-Sigarroa Eduardo, Loeza-Guemez Alejandro.

Authors: Carrillo-Torres Orlando [1], Rivero-Sigarroa Eduardo [1], Loeza-Guemez Alejandro[1].

[1] Department of anesthesiology of the Hospital General de México “Dr. Eduardo Liceaga”.

Address of Correspondence

Dr. Orlando Carrillo Torres,

Av. Cuauhtemoc 590, Narvarte Poniente Benito Juarez. CxMx CP 03020


Introduction: Anaplastic large cell lymphoma (ALCL), which was first described by Stein in 1985 as a feature of CD30 positivity, is now acknowledged as a distinct subset of T-cell non-Hodgkin lymphomas (NHL). It accounts for approximately 3% of adult NHL while constitutes as many as 30%–40% of pediatric large-cell lymphomas. It is rarely metastasized to other sites, especially to the central nervous system (CNS).

Case Report: We present a case of a 73-year-old woman hospitalized for fever, acute behavioral changes, and progressive neurological degeneration; a rare case of systemic ALCL which metastasized to the brain. There are very few case reports of this matter in the literature.

Conclusion: In the management of patients with neurological impairment, cognitive, and behavioral changes, we suspect the presence of lymphomas associated with the CNS still suspicious of other primary causes.

Keywords: Anaplastic large-cell lymphoma, anaplastic lymphoma kinase gene, primary central nervous system lymphoma, non-Hodgkin lymphoma, T-cell lymphoma, lymph node enlargement.


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How to Cite this Article: Orlando CT, Eduardo RS, Alejandro LG. Case Report: A Woman with Fever, Acute Changes in Mental State, and Progressive Neurological Degeneration. Journal of Anaesthesia and Critical Care Case Reports Sep-Dec 2018; 4(3):17-20.

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